Photobiomodulation, PBM Therapy, reduces inflammation and improves healing including 32 controlled clinical trials demonstrating PBM Therapy as an effective method of treating Oral Mucositis.
Patients undergoing cancer treatments – chemotherapy, radiotherapy or haematopoietic stem cell transplantation (HSCT) – in both paediatric and adult populations are at extreme risk of developing Oral Mucositis (OM) and radiation dermatitis. For some treatments unfortunately it’s almost a 100% certainty the patient will develop this painful condition. It is due to the fact that cancer drugs attack rapidly dividing cancer cells but they also attack the rapidly dividing epithelial cells lining the mouth and gastro-intestinal tract.
The moist linings become highly swollen, red, ulcerated and acutely painful so that even swallowing water, let alone food can become a real problem. PBM Therapy for Oral Mucositis has been reported in 32 randomised controlled clinical trials. Most of the studies are therapeutic (treating symptoms) proving PBM Therapy reduces the severity and duration of Oral Mucositis, but some clinical trials have also shown that treatment concurrent with cancer therapies can be used for prevention. This is clearly a real benefit because it means patients can eat and drink easier which helps to maintain their health whilst they receive these treatments.
**STOP PRESS **
In one recent trial (RCT) the study was stopped prematurely because the nurses and clinicians delivering the treatment could not ethically carry on as it was clear the patients who were receiving the PBM Therapy were so much better. The clinicians felt they could not deny this treatment to the control group (placebo group). The trial was stopped to allow all the patients to receive PBM Therapy.